Principal Scientist RNA
Company: Takeda Pharmaceutical
Location: El Cajon
Posted on: May 12, 2022
Job Description:
By clicking the "Apply" button, I understand that my employment
application process with Takeda will commence and that the
information I provide in my application will be processed in line
with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionOBJECTIVES/PURPOSE Takeda is seeking an
experienced Principal Scientist to join our Drug Discovery Sciences
(DDS) department. You will lead RNA target identification and hit
identification efforts. - You will have a strong record in driving
drug discovery programs and stablishing effective in-vitro hit
finding and target validation assay strategies. - You will build
robust collaborations with internal and external partners, and work
effectively with biophysicists, structural biologists, chemists,
computational chemists and biologists to advance drug discovery
programs. You will apply a creative and innovative mindset to
identify and solve critical scientific and technical challenges.You
will become an integral member of an international, highly
multidisciplinary, and science-driven team committed to help
patients by delivering innovative therapies against hard-to-drug
diseases.Leadership/People:No. of direct reports:
1-2ACCOUNTABILITIES - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
- - - - -
- Design and implement effective hit identification and
validation strategies using biochemical and cell based assays to
accelerate small molecule-RNA programs
- Generate luminescence-based/fluorescence-based mammalian
reporter assays (endogenous reporter, minigene reporter,
overexpression system, gene KO system) using transient
transfection/stable transduction
- Develop and optimize cellular assays using biochemical or
imaging-based readouts in a low, medium, or high throughput format
for target validation and hit characterization
- Manage resources effectively to accelerate multiple programs
simultaneously
- Rigorous data analysis and interpretation
- Develop innovative approaches for the study of RNA
modulatorsTechnical/Functional (Line) Expertise
- Demonstrate well-developed knowledge of related areas such as
protein chemistry, cell biology and biophysics
- Strong understanding of the drug discovery processLeadership
- Design and direct research strategy and activities to meet
program objectives; provide leadership, timelines and contingency
plans - - - - - - - - - - - -Decision-making and Autonomy
- Independently manage workload and expectations
- Scientifically independent
- Scientific driver for research strategy that impacts group
internally and outside area of function -Interaction
- Initiate and lead external interactions and collaborations
- Frequent contact with internal and external personnel at
various management levels
- Collaborate with other departments, and disciplines, acting as
scientific authority within discipline
- Serve as senior company / project representative at external
conferences, or business meetingsEDUCATION, BEHAVIOURAL
COMPETENCIES AND SKILLS: -
- PhD degree in a scientific discipline with 8+ years experience
, or
- MS with 12+ years experience, or
- BS with 14+ years experienceIn accordance with the CO Equal Pay
Act, -Colorado Applicants Are Not Permitted to Apply.EEO
StatementTakeda is proud in its commitment to creating a diverse
workforce and providing equal employment opportunities to all
employees and applicants for employment without regard to race,
color, religion, sex, sexual orientation, gender identity, gender
expression, parental status, national origin, age, disability,
citizenship status, genetic information or characteristics, marital
status, status as a Vietnam era veteran, special disabled veteran,
or other protected veteran in accordance with applicable federal,
state and local laws, and any other characteristic protected by
law.LocationsSan Diego, CAWorker TypeEmployeeWorker
Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, El Cajon , Principal Scientist RNA, Other , El Cajon, California
Didn't find what you're looking for? Search again!
Loading more jobs...